Increased migration and motility in xiap-null cells mediated by the c-raf protein kinase

HIGHLIGHTS

  • who: Lauren G. Russell from the Newcastle University have published the research: Increased migration and motility in XIAP-null cells mediated by the C-RAF protein kinase, in the Journal: Scientific Reports Scientific Reports of 11/04/2022
  • what: The authors show that chemical inhibition of C-RAF reverses the enhanced cell migration observed in XIAP-null cells.
  • how: The authors therefore decided to use XIAP-null cells to investigate if genetic deletion of the XIAP gene alters migration rates in U2OS cells.

SUMMARY

    To investigate what properties of . . .

     

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