HIGHLIGHTS
- who: Therapies and collaborators from the Rensselaer Polytechnic Institute, Troy, NY, United States University of Catania, Italy have published the article: Mathematical Modeling of Complement Pathway Dynamics for Target Validation and Selection of Drug Modalities for Complement Therapies, in the Journal: (JOURNAL)
- what: For refining the model dynamics and estimating the kinetic parameters, several published and in-house in_vitro datasets were used for validation of the dynamics of alternative and terminal pathways. The quantitative implementation for the role of Properdin in the activation of the alternative pathway is based on the model proposed by Hourcade . . .
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