Structures and comparison of endogenous 2-oxoglutarate and pyruvate dehydrogenase complexes from bovine kidney

HIGHLIGHTS

  • who: Shiheng Liu from the (UNIVERSITY) have published the Article: Structures and comparison of endogenous 2-oxoglutarate and pyruvate dehydrogenase complexes from bovine kidney, in the Journal: (JOURNAL)
  • what: The authors report the cryo-electron microscopy structures of the endogenous cubic dehydrogenase complex (OGDC) and icosahedral pyruvate dehydrogenase complex (PDC) cores from bovine kidney determined at resolutions of 3.5 u00c5 and 3.8 u00c5 respectively. Taken together the study provides a direct structural comparison of OGDC and PDC from the same source and offers new insights into determinants of interdomain interactions and of architecture . . .

     

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