Molecular features and diagnostic challenges in alpha/beta t-cell large granular lymphocyte leukemia

HIGHLIGHTS

  • who: Francesco Gaudio et al. from the Hematology Section, Department of Emergency and Transplantation, University of Bari Medical School, Bari, Italy have published the research work: Molecular Features and Diagnostic Challenges in Alpha/Beta T-Cell Large Granular Lymphocyte Leukemia, in the Journal: (JOURNAL)
  • what: __SECTION__ 9. Conclusions.

SUMMARY

    Large granular lymphocytes (LGL) are a morphologically distinct subpopulation of peripheral blood mononuclear cells, which normally account for 10-15% of peripheral blood mononuclear cells. Molecular analysis of the clonal repertoire of the T-cell receptor (TCR) in LGL leukemia is important . . .

     

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