HIGHLIGHTS
SUMMARY
Hypercalcemia is an infrequent finding in children. In the differential diagnosis of hypercalcemia, two categories must be considered: PTH-dependent (parathyroid adenoma or carcinoma, familial primary hyperparathyroidism, multiple endocrine neoplasia (MEN) types I, IIa, IV, tertiary hyperparathyroidism) and PTH-independent (drugs, Addison`s disease, pheochromocytoma, malignancies, inborn errors of metabolism, tubular acidosis). In the child or adolescent, PH is usually sporadic (65%), and it is due to a single parathyroid adenoma (80%-92%); rarely, parathyroid adenoma occurs as a part of MEN syndromes. The clinical features of hypercalcemia may be nonspecific and depend upon . . .
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