Nuclear soluble cgas senses double-stranded dna virus infection

HIGHLIGHTS

• who: Yakun Wu from the Tulane University have published the research: Nuclear soluble cGAS senses double-stranded DNA virus infection, in the Journal: (JOURNAL) of 18/01/2022
• how: By contrast transfected ctDNA failed to activate innate immune response in KO(LL/RK-NLS) RAW264.7 macrophages (Supplementary Fig 5b) suggesting that is activated by HSV-1 infection but not Next the authors examined whether enzymatic activity was required for cGAS-mediated innate immune ARTICLE Fig 4 Generation of a stable cell line exclusively expressing a HEK293 cells stably expressing mouse fused with a C . . .
  

   

  

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