Shared genetic links between frontotemporal dementia and psychiatric disorders

HIGHLIGHTS

  • who: Chunyu Li from the (UNIVERSITY) have published the article: Shared genetic links between frontotemporal dementia and psychiatric disorders, in the Journal: (JOURNAL)
  • what: A genetic pleiotropic conditional false discovery rate (FDR) approach was developed to investigate genetic overlap between polygenic traits using summary data from GWAS and has been utilized extensively in several human traits and diseases . Applying this approach, the authors systematically evaluated the shared genetic background between FTD and psychiatric disorders and further conducted functional enrichment analysis and Mendelian randomization (MR) analysis, as was shown in the graphical abstract. The authors identified . . .

     

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