Cell-penetrating peptide-conjugated copper complexes for redox-mediated anticancer therapy

HIGHLIGHTS

  • who: . et al. from the Jilin University, China have published the research: Cell-penetrating peptide-conjugated copper complexes for redox-mediated anticancer therapy, in the Journal: (JOURNAL)
  • what: Nonetheless, most Cu- and other metal-related biological pathways, including catalytic processes to Frontiers in Pharmacology frontiersin.org 10.3389/fphar.2022.1060827 with the main goal of increasing solubility in aqueous media, namely the addition of a sulfonate group (ligand H2L2 and complex C2), and of an arginine (Arg) residue (ligand H2L3 and complex C3) . For that purpose, ligand H2L1 was functionalized with a sulfonate group . . .

     

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