Properties of nav1.8

HIGHLIGHTS

  • who: Akihiro Yamada from the Department of Anesthesiology and Perioperative Medicine, School of Medicine, University of Alabama at Birmingham, Birmingham, AL, USA have published the research: Properties of Nav1.8, in the Journal: (JOURNAL)
  • what: The authors generated mice expressing channel rhodopsin 2 (ChR2) in Nav1.8-positive afferents (Nav1.8ChR2) which showed avoidance responses to stimulation and nocifensive responses to blue light stimulation applied to hindpaws. The study shows that Nav1.8cre mouse line labels almost all C-fibers, whereas C u00adGRPcre and u00ad TRPV1cre mouse lines label subpopulations of nociceptive C-afferents. In . . .

     

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