Moxonidine increases uptake of oxidised low-density lipoprotein in cultured vascular smooth muscle cells and inhibits atherosclerosis in apolipoprotein e-deficient mice

HIGHLIGHTS

  • who: Yutang Wang and collaborators from the Institute Innovation, and Sustainability, Federation University Australia have published the article: Moxonidine Increases Uptake of Oxidised Low-Density Lipoprotein in Cultured Vascular Smooth Muscle Cells and Inhibits Atherosclerosis in Apolipoprotein E-Deficient Mice, in the Journal: (JOURNAL)
  • what: The current study, for the first time, showed that incubation with moxonidine stimulated VSMC migration that potentially contributes to plaque stabilisation. This study did not investigate the effect of moxonidine on endothelial function and this needs to be investigated in the future. The authors propose the following mechanism to explain . . .

     

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