HIGHLIGHTS
- who: Shuang Zhang from the State Key Laboratory of Quality Research in Chinese Medicine, Institute of Chinese Medical Sciences, University of Macau, Taipa, Macau SAR, China have published the research work: Toosendanin, a late-stage autophagy inhibitor, sensitizes triple-negative breast cancer to irinotecan chemotherapy, in the Journal: (JOURNAL)
- what: The authors reported that TSN potently inhibited auto-lysosome maturation, leading to the accumulation of autophagosomes in TNBC cells. When checking the experiment data, no autophagy flux assay was applied in the study thus the interpretation of the results could be problematic. The authors provided . . .
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