Enteroendocrine cell formation is an early event in pancreatic tumorigenesis

HIGHLIGHTS

  • who: Tumorigenesis et al. from the Department of Cell and Developmental Biology, Vanderbilt University, Nashville, TN, United States, Department of Pathology have published the article: Enteroendocrine Cell Formation Is an Early Event in Pancreatic Tumorigenesis, in the Journal: (JOURNAL)
  • what: The authors demonstrate that tuft cell master regulator transcription factor, POU2F3, is not required for EEC formation (Yamaguchi et_al, 2014; Gerbe et_al, 2016). The authors report the presence of GHRL+ epsilon cells within the peribiliary glands of the pancreatobiliary duct, a glandular structure reported to serve as a possible progenitor niche, as well Frontiers in . . .

     

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