Subclinical infection occurs frequently following low dose exposure to prions by blood transfusion

HIGHLIGHTS

  • who: M. Khalid F. Salamat from the The Roslin Institute University of have published the paper: Subclinical infection occurs frequently following low dose exposure to prions by blood transfusion, in the Journal: Scientific Reports Scientific Reports
  • what: The authors have shown that a high proportion of sheep transfused with blood components from BSE-infected preclinical donors may survive for more than 10 years (i.e. close to their expected lifespan) without developing clinical signs of disease, yet harbour u00adPrPSc in lymph nodes that is detectable using a sensitive amplification assay (PMCA).
  • how: To . . .

     

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