Mtx-peg-modified cg/dmma polymeric micelles for targeted delivery of doxorubicin to induce synergistic autophagic death against triple-negative breast cancer

HIGHLIGHTS

  • who: Zhiwen Cao from the (UNIVERSITY) have published the Article: MTX-PEG-modified CG/DMMA polymeric micelles for targeted delivery of doxorubicin to induce synergistic autophagic death against triple-negative breast cancer, in the Journal: (JOURNAL)
  • what: Given that, the authors propose a hypothesis that ingeniously designed synergistic therapy might emerge as an efficient strategy for interfering with the multistep process of autophagy to induce autophagic death on tumor cell itself and escaping the degradation on drugs. In the present study, nano-scaled polymeric micelles were designed for targeted delivery of DOX to reduce toxicity . . .

     

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