Molecular determinants regulating the plasticity of the mhc class ii immunopeptidome

HIGHLIGHTS

• who: Laura Santambrogio from the Department of Radiation Oncology, Weill Cornell Medicine, New York, NY, United States, Sandra and Edward Meyer Stanford University, United States have published the article: Molecular Determinants Regulating the Plasticity of the MHC Class II Immunopeptidome, in the Journal: (JOURNAL) of 17/02/2022
• what: In the last decade, many studies have converged in defining the composition of the MHC-II ligandome at steady_state and during pathological conditions.

SUMMARY

Lack of MHC-II expression results in severe compromise of CD4+ T_cell development and a consequent fatal immunodeficiency . . .

 



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