HIGHLIGHTS
- who: Bingqing Luo from the (UNIVERSITY) have published the research: Myelodysplastic syndromes are multiclonal diseases derived from hematopoietic stem and progenitor cells, in the Journal: (JOURNAL)
- what: The authors aimed to identify the cell of origin in MDS by single-cell analyses.
SUMMARY
Single-cell sequencing but not bulk sequencing detects the co-occurrence of mutations in the same cells, permitting to distinguish individual clones from one another. Three mutations detected in both the HD and MDS groups were termed CH mutations while the remaining fifteen mutations only detected in MDS . . .
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