HIGHLIGHTS
- who: Jianhua Wei from the (UNIVERSITY) have published the article: Endowing homodimeric carbamoyltransferase GdmN with iterative functions through structural characterization and mechanistic studies, in the Journal: (JOURNAL) of 16/02/2022
- what: To generate an iterative CTase, the authors determine the X-ray structure of GdmN, a one-step CTase involved in ansamycin biosynthesis. The authors examine the molecular structure of the ansamycin-modifying CTase GdmN, with the goals of repurposing this enzyme for the iterative carbamoylation of ansamitocins.
- how: The results showed that the conversion from 2 to 3 in the presence . . .
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