Transglutaminase 2 affinity and enzyme‐substrate intermediate stability as determining factors for t‐cell responses to gluten peptides in celiac disease

HIGHLIGHTS

• who: Sunniva F. Amundsen et_al and collaborators from the KG Jebsen Coeliac Disease Research Centre, Institute of Clinical Medicine, University of have published the research: Transglutaminase 2 affinity and enzymeu2010substrate intermediate stability as determining factors for Tu2010cell responses to gluten peptides in celiac disease, in the Journal: (JOURNAL)
• what: The authors have examined how gluten peptide affinity to TG2 affects the crosstalk between TG2-specific B cells and gluten-specific T_cells, and the authors have further addressed how natural small_molecule primary amines affect the B-cell mediated presentation of gluten peptides to T_cells. B-cell . . .
  

   

  

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