HIGHLIGHTS
- who: Huai-liang Wu from the (UNIVERSITY) have published the research work: Targeting nucleotide metabolism: a promising approach to enhance cancer immunotherapy, in the Journal: (JOURNAL)
- what: The authors review how dysregulated can promote tumor growth and interact with the host immune system and the authors provide future insights into for immunotherapeutic treatment of various malignancies.
SUMMARY
Have been reported, the key enzymes and regulatory mechanisms involved in nucleotide metabolism remain unclear. All classical antitumor drugs inhibiting nucleotide synthesis are based on analogs of tumor nucleotide metabolites and have previously served . . .
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