An integrative bioinformatics analysis of the potential mechanisms involved in propofol affecting hippocampal neuronal cells

HIGHLIGHTS

• who: Zhao Zhuang and colleagues from the Medical University, China have published the Article: An Integrative Bioinformatics Analysis of the Potential Mechanisms Involved in Propofol Affecting Hippocampal Neuronal Cells, in the Journal: Computational Intelligence and Neuroscience of 26/04/2022
• what: The study showed that propofol sedation can affect mRNA expression in the hippocampus providing new ideas to identify treatment nerve injury induced by propofol anesthesia. In the present experiment, the authors performed GSEA analyses of individual genes separately and showed that CD86, IL10RA, PTPRC, SPI1, and ITGAM are involved in the PRION_DISEASES pathway.
 



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