Inadequate activation of γδt- and b-cells in patient with wiskott-aldrich syndrome (was) portrayed by trg and igh repertoire analyses

HIGHLIGHTS

  • who: Dahlia Palevski from the Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel have published the research: Inadequate Activation of u03b3u03b4T- and B-cells in Patient with Wiskott-Aldrich Syndrome (WAS) Portrayed by TRG and IGH Repertoire Analyses, in the Journal: (JOURNAL)
  • what: The authors demonstrate by analyzing the based on genomic DNA the various effect that WAS mutations have in shaping the TRG and IGH adaptive immune repertoires. Since T-cell receptor gamma (TRG) expressing u03b3u03b4T-cells are elevated in the peripheral blood in patients with asthma, allergic rhinitis, and skin eczema . . .

     

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