In vivo dissection of a clustered-ctcf domain boundary reveals developmental principles of regulatory insulation

HIGHLIGHTS

  • who: Chiara Anania from the Berlin Institute have published the article: In vivo dissection of a clustered-CTCF domain boundary reveals developmental principles of regulatory insulation, in the Journal: (JOURNAL) of 27/04/2021
  • what: The authors show chromatin boundaries are modular and constitute multicomponent genomic regions subjected to several regulatory principles.
  • how: The authors explored whether these nonconvergent loops could be explained by the nonconvergent anchor simultaneously establishing a convergent loop in the opposite direction (Fig 3a).

SUMMARY

    Received Published online: 11 July 2022 @@

ACRONYMS

     

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