Arylamine n-acetyltransferase 1 deficiency inhibits drug-induced cell death in breast cancer cells: switch from cytochrome c-dependent apoptosis to necroptosis

HIGHLIGHTS

  • who: Courtney E. McAleese from the School of Biomedical Sciences, The University of Queensland, Brisbane, QLD, Australia have published the research: Arylamine N-acetyltransferase 1 deficiency inhibits drug-induced cell death in breast cancer cells: switch from cytochrome C-dependent apoptosis to necroptosis, in the Journal: (JOURNAL)
  • what: This study aimed to investigate in vitro using normal cell lines and NAT1-deficient cell lines to understand the changes induced by the lack of that resulted in poor response. This study was designed to investigate whether NAT1 deficiency seen in a significant proportion of breast tumours . . .

     

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