Small but strong: pivotal roles and potential applications of snornas in hematopoietic malignancies

HIGHLIGHTS

  • who: Jian Dong from the University of Arizona, United States have published the Article: Small but strong: Pivotal roles and potential applications of snoRNAs in hematopoietic malignancies, in the Journal: (JOURNAL)

SUMMARY

    Hematopoiesis is the essential physiological process of maintaining the blood system, which relies on a small population of cells that can differentiate into blood progenitor cells and self-renew, namely, hematopoietic stem_cells (HSCs). Impairment of the cells lacking five snoRNAs (-6Ys) was more severe than that observed for loss of the Y2919 guide snoRNA alone, suggesting the possibility of synergy between . . .

     

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