Plasmodium falciparum molecular chaperones: guardians of the malaria parasite proteome and renovators of the host proteome

HIGHLIGHTS

  • who: Francesco Fazi and colleagues from the Sapienza University of Rome, Italy have published the article: Plasmodium falciparum Molecular Chaperones: Guardians of the Malaria Parasite Proteome and Renovators of the Host Proteome, in the Journal: (JOURNAL)

SUMMARY

    Interestingly, an unusually high proportion of P. falciparum proteins (24-30%) are rich in asparagine (N) and glutamine (Q), particularly poly-N repeats (Singh et_al, 2004; Pallarès et_al, 2018), which have been found to have a tendancy to aggregate (Halfmann et_al, 2011). Like PfHsp70-3, other PfHsp70s (PfHsp70-1, PfHsp70-z, and PfHsp70-x) have . . .

     

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