The protease ddi2 regulates nrf1 activation in response to cadmium toxicity

HIGHLIGHTS

  • who: Su00e9rgio T. Ribeiro from the of Immunobiology, University of Lausanne, Chdes Boveresses, Epalinges, Switzerland have published the article: The protease DDI2 regulates NRF1 activation in response to cadmium toxicity, in the Journal: (JOURNAL) of October/21,/2022
  • what: In agreement with the in -vivo data where the authors demonstrate that MT activation is independent of NRF2 activity, the chemical activation of NRF2 with tert-butylhydroquinone (tBHQ) treatment did not induce the MT-promoter activation in HepG2 cells . -This study reports a mouse model to investigate DDI2-associated molecular mechanisms and physiological functions. These data . . .

     

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