HIGHLIGHTS
SUMMARY
The authors observed that the relative fractions of regulatory T_cells, M0 macrophages, M2 Ferroptosis-Related Gene Signature Related to Immune Cell Infiltration There were no significant differences in gamma delta T_cells, resting NK cells, activated NK cells, or dendritic cell infiltration between the two groups. According to Wang, immunotherapy-activated CD8+ T_cells aggravated ferroptosisspecific lipid peroxidation, thereby enhancing immunotherapy`s anti-tumor efficacy. Previous studies have revealed that SMAD7 acts as a tumor suppressor in a variety of cancers, including gastric cancer, Frontiers in Oncology | www.frontiersin.org July 2022 | Volume 12 | Article 933925 . . .
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