Is the serotonin hypothesis dead? if so, how will clinical psychology respond?

HIGHLIGHTS

SUMMARY

    Frontiers in Psychology serotonin hypothesis, affective disorders, depression, clinical psychologists, medication For decades models of mental illness, particularly depression, have been influenced by the serotonin hypothesis (Coppen, 1967; Fakhoury, 2016). This model is the primary justification for the prescription of selective serotonin reuptake inhibitors (SSRIs; e_g, Prozac, Zoloft, Lexapro ). SSRI prescription is extremely popular within modern psychiatry, with an estimated 13% of people living in the United_States having taken an SSRI within the past 30 days (Brody and Gu, 2020). World-wide estimates are difficult to obtain, but developed European nations report commensurate prescribing . . .

     

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