Spatial organization of hydrophobic and charged residues affects protein thermal stability and binding affinity

HIGHLIGHTS

  • who: Fausta Desantis from the Center for LifeSapienza University have published the Article: Spatial organization of hydrophobic and charged residues affects protein thermal stability and binding affinity, in the Journal: Scientific Reports Scientific Reports
  • what: The authors propose a comprehensive investigation and comparison between those aspects with respect to fold and binding stability. In the next section, the authors provide a brief summary of the main features of the Zernike basis.
  • how: Next the authors compared the measured energies with experimental data of melting temperature and binding affinity for the Tm and Ba . . .

     

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