HIGHLIGHTS
- who: OPINION and collaborators from the Tongji University Cancer Center, Shanghai Tenth People`s Hospital, School of Medicine, Tongji University, Shanghai, China have published the article: Phase Separation in Regulation of Autophagy, in the Journal: (JOURNAL)
SUMMARY
The hallmark of autophagy is autophagosome formation, which involves nucleation, expansion, and closure of the phagophore (Melia et_al, 2020; Nakatogawa, 2020). The lipid transporter ATG2, the scramblase ATG9 and lipidated ATG8 proteins contribute to phagophore expansion, and the ESCRT machineries are recruited to finalize the closure to form an intact autophagosome (Mizushima et_al, 2011; Hurley and . . .
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