Menadione potentiates auranofin-induced glioblastomacell death

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  • who: Monika Szeliga and Radosu0142aw Rola from the Department of Neurotoxicology, Mossakowski Medical Research Institute, Polish Academy of Sciences, Pawinu0301skiego Str, Warsaw, Poland Department of Neurosurgery and Paediatric Neurosurgery, Medical University of Lublin have published the Article: Menadione Potentiates Auranofin-Induced GlioblastomaCell Death, in the Journal: (JOURNAL)
  • what: The authors focused on TrxR1, regarded as one of the master regulators of cellular redox homeostasis, due to its central role in cytosolic H2 O2 detoxification. The authors show that 10 u00b5M MEN alone slightly decreases viability of both GBM cell lines and patient-derived cells. All . . .

     

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