Cd95 gene deletion may reduce clonogenic growth and invasiveness of human glioblastoma cells in a cd95 ligand-independent manner

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  • who: Clara Quijano-Rubio from the (UNIVERSITY) have published the article: CD95 gene deletion may reduce clonogenic growth and invasiveness of human glioblastoma cells in a CD95 ligand-independent manner, in the Journal: (JOURNAL) of 14/05/2022
  • what: Although it has been argued that tumorpromoting CD95 signaling is exclusive to cells resistant to CD95mediated apoptosis , the authors demonstrate that CD95 mediates clonogenic growth, sphere formation, and invasion in human GIC that are intrinsically sensitive to CD95L-induced apoptosis (Fig 3).
  • how: The authors explored the role of constitutive CD95 signaling in human . . .

     

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