HIGHLIGHTS
SUMMARY
Conversely, "maladaptive remodelling" refers to shape and size changes occurring due to an adverse cycle of metabolic and structural changes resulting in heart failure. Biventricular atlases have enabled analysis of the RV and left ventricular (LV) shape changes simultaneously, enabling the detection of anomalous patterns of biventricular inter-relationships. Although previous studies have focused on surrogate markers such as pulmonary regurgitation volume index (PRVI) to characterise adverse remodelling, using surrogate endpoints as intermediate indicators of adverse outcomes may overlook important shape-related information associated with adverse remodelling but not captured by the surrogate marker . . .
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