HIGHLIGHTS
- who: Tiantian Liu et al. from the Sichuan University, China have published the paper: TERT promoter mutations and methylation for telomerase activation in urothelial carcinomas: New mechanistic insights and clinical significance, in the Journal: (JOURNAL)
- how: The obtained results showed that urine-DNA testing could identify a large subgroup of patients with hematuria in whom cystoscopy is not required.
- future: Clinical investigations are required to determine whether the C250T-related BCG efficacy results from altered TERT expression or from other direct and indirect activities.
SUMMARY
In 2013, two seminal . . .
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