Enzymatic methods for mutation detection in cancer samples and liquid biopsies

HIGHLIGHTS

  • who: Farzaneh Darbeheshti and G. Mike Makrigiorgos from the Department of Radiation Oncology, Dana Farber Cancer Institute, Brigham and Women`s Hospital, Harvard Medical School, Boston, MA, USA have published the research: Enzymatic Methods for Mutation Detection in Cancer Samples and Liquid Biopsies, in the Journal: (JOURNAL)
  • what: Enzymatic-based mutation enrichment methods have evolved through the years from the traditional approaches using restriction_endonucleases that detect a minority of mutations to newer methods using a variety of different enzymes that can detect all mutations on multiple targets simultaneously.
  • how: This review describes traditional . . .

     

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