HIGHLIGHTS
- who: Guillermo A. Martí from the University of Patras, Greece have published the paper: Upregulated integrin u03b111 in the stroma of cutaneous squamous cell carcinoma promotes skin carcinogenesis, in the Journal: (JOURNAL)
- what: In this analysis, cSCC was characterized by the high expression of CAF and epithelial-to-mesenchymal (EMT) markers PDGFRb, aSMA, podoplanin, Zeb1, Slug, and Twist . The authors report the novel findings on the notable upregulation of integrin a11 expression in the stromal compartment of human and mouse cSCCs, as well as the significant impairment of DMBA/TPA-induced skin tumor growth . . .
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