Prostate cancer stem cells: clinical aspects and targeted therapies

HIGHLIGHTS

  • who: Isis Wolf from the Department of Urology, Medical Center-University of Freiburg, Freiburg, Germany, Faculty of Medicine, University of have published the article: Prostate Cancer Stem Cells: Clinical Aspects and Targeted Therapies, in the Journal: (JOURNAL)
  • what: There is emerging knowledge about the role of PCSCs, and new therapeutic approaches aim to achieve an improved therapeutic outcome.
  • how: Specific inhibitors against the Hh pathway (Sonidegib GANT-61 and GDC-0449) the Wnt pathway (3289-8625 LGK974 Foxy-5 and OMP-54F28) the Notch pathway (RO4929097) and the NFkB pathway are tested in . . .

     

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