Synthesis, antitumor evaluation and computational study of thiazolidinone derivatives of dehydroabietic acid-based b ring-fused-thiazole

HIGHLIGHTS

• who: Posted Date January et al. from the Guangxi Medical University have published the paper: Synthesis, antitumor evaluation and computational study of thiazolidinone derivatives of dehydroabietic acid-based B ring-fused-thiazole, in the Journal: (JOURNAL)
• what: 15 new thiazolidinone derivatives of dehydroabietic acid-based B ring-fused-thiazole were synthesized and their in_vitro cytotoxic activities were investigated by CCK-8 assay against SCC9, Cal27 and SAS.
• how: These results indicated that integrated arylidene groups could enhance the antitumor activities against SCC9 and Cal27 but showed opposite effect against SAS cell line. These . . .
  

   

  

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