Gpcr/endocytosis/erk signaling/s2r is involved in the regulation of the internalization, mitochondria-targeting and -activating properties of human salivary histatin 1

HIGHLIGHTS

• who: Dandan Ma from the DepartmentUniversity of have published the research: GPCR/endocytosis/ERK signaling/S2R is involved in the regulation of the internalization, mitochondria-targeting and -activating properties of human salivary histatin 1, in the Journal: (JOURNAL) of 27/Dec/2021
• what: The authors investigated the influence of specific inhibitors of GPCR, various endocytosis pathways, ERK signaling, p38 signaling, an inhibitor of mitochondrial respiration, and an inhibitor of Na+/K+-ATPase activity as well as siRNA knockdown (KD) of S2R/TMEM97 on the mitochondria-targeting and -activating properties of Hst1. The authors aimed to . . .
  

   

  

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