HIGHLIGHTS
- who: VEGF et al. from the King Saud University, Saudi Arabia have published the research work: Effect of troxerutin in hyperglycemia-induced VEGF upregulation in endothelial cells: a new option to target early stages of diabetic retinopathy?, in the Journal: (JOURNAL)
- what: In this regard, the authors show here that, remarkably, troxerutin is able to preempt the hyperglycemiainduced increase in VEGF in both in_vitro models, thus suggesting its potential use in DR. It seems that troxerutin ameliorates diabetic retinopathy by downregulating neoangiogenesis factors as well as hindering free_radical production, since the latter plays a central . . .
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