HIGHLIGHTS
- who: . et al. from the Laval University, Canada have published the article: Exercise alleviates diabetic complications by inhibiting oxidative stress-mediated signaling cascade and mitochondrial metabolic stress in GK diabetic rat tissues, in the Journal: (JOURNAL)
- what: The study shows that exercise significantly improves redox homeostasis, glucose uptake, and energy metabolism, improves mitochondrial function, and possibly increases insulin sensitivity by activation of the AMPK/SIRT1/PPAR-u03b3 pathways.
SUMMARY
For cellular fractionation, the tissues were homogenized in H-medium (70 mM sucrose, 220 mM mannitol, 2.5 mM HEPES, 2 mM . . .
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