HIGHLIGHTS
- who: ROS and colleagues from the University of Missouri, United States have published the Article: Insights from DOCK2 in cell function and pathophysiology, in the Journal: (JOURNAL)
- what: The authors aim to mainly present a review of DOCK2 in immune cells and various diseases.
SUMMARY
DOCK2 deficiency reduces the number and proportion of T_cells in the lymph nodes and spleens and affects T_cell development (Fukui et_al, 2001; Terasawa et_al, 2012). DOCK2 regulates development and activation of B lymphocytes, as well as affects plasma cell differentiation (Wang et_al, 2017; Ushijima et_al, 2018 . . .
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