Discovery of small molecule mechanistic target of rapamycin inhibitors as anti-aging and anti-cancer therapeutics

HIGHLIGHTS

• who: Zofia Chrienova from the Centre National de la Recherche (CNRS), France Complutense University, Spain have published the research: Discovery of small molecule mechanistic target of rapamycin inhibitors as anti-aging and anti-cancer therapeutics, in the Journal: (JOURNAL)
• what: Tested in long-lived, genetically heterogenous mice, in which it extends both mean and maximum lifespans.
• how: Data were analyzed using FlowJo 10 software (FlowJo LLC Ashland OR USA). Docking results showed that compound 1 exerts the following binding mode benzimidazole ring occupied the same place as the adenine ring of ATP concurrently . . .
  

   

  

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