Albumin-mediated size exclusion chromatography: the apparent molecular weight of psma radioligands as novel parameter to estimate their blood clearance kinetics

HIGHLIGHTS

• who: Jan-Philip Kunert and collaborators from the Department Chemistry, Technical University Munich (TUM), Garching, Germany have published the research: Albumin-Mediated Size Exclusion Chromatography: The Apparent Molecular Weight of PSMA Radioligands as Novel Parameter to Estimate Their Blood Clearance Kinetics, in the Journal: Pharmaceuticals 2022, 1161 of 19/09/2022
• what: 3 of 22 With respect to these considerations, the authors aim to develop a method based on size exclusion chromatography (SEC) that not only allows to merely determine the binding of radioligands to HSA but also to possibly deduce conclusions on radioligand blood . . .
  

   

  

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