Genetic mouse models to study pancreatic cancer-induced pain and reduction in well-being

HIGHLIGHTS

• who: Michael Hirth et al. from the Pharmacology Institute, Medical Faculty Heidelberg, Heidelberg University, Heidelberg, Germany have published the article: Genetic Mouse Models to Study Pancreatic Cancer-Induced Pain and Reduction in Well-Being, in the Journal: Cells 2022, 2634 of /2022/
• what: The authors demonstrate that the mouse model is best suited to studying cancer pain whereas the model can be employed to study cancer-associated reduction in well-being. In the current work, the authors characterized the KPC (KrasG12D/+; Trp53R172H/+; P48-Cre) and KPPC mouse models (KrasG12D/+; Trp53R172H/R172H; P48-Cre), which represent . . .
  

   

  

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