The pseudokinase nrbp1 activates rac1/cdc42 via p-rex1 to drive oncogenic signalling in triple-negative breast cancer

HIGHLIGHTS

  • who: Xue Yang from the Cell lines and tissue culture HEK T and Plat-E cells were maintained in Dulbecco`s Modified Eagle`s Medium (DMEM, Gibco, cat1200046) supplemented with, % (v/v) fetal bovine serum (FBS have published the research work: The pseudokinase NRBP1 activates Rac1/Cdc42 via P-Rex1 to drive oncogenic signalling in triple-negative breast cancer, in the Journal: (JOURNAL) of 24/01/2023
  • what: The authors identified NRBP1 via a proteomics screen in TNBC and then characterized its function and signalling mechanism in detail. Utilizing diverse functional assays, both in_vitro and . . .

     

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