Escape from x-inactivation in twins exhibits intra- and inter-individual variability across tissues and is heritable

HIGHLIGHTS

• who: Antonino Zito and collaborators from the Editor: SBartolomei, University of have published the article: Escape from X-inactivation in twins exhibits intra- and inter-individual variability across tissues and is heritable, in the Journal: (JOURNAL) of February/21,/2023
• what: The authors characterize XCI escape using paired bulk RNAseq and DNAseq data in a multitissue dataset sampled from 248 skewed female twins of the TwinsUK bioresource . The authors investigate escape prevalence and variability across adipose and skin tissue, lymphoblastoid cell lines and purified immune cells (monocytes, B-cells, T-CD4+, T-CD8+ and NK . . .
  

   

  

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