Efficacy decrease of antiviral agents when administered to ongoing hepatitis c virus infections in cell culture

HIGHLIGHTS

  • who: Esteban Domingo and Celia Perales from the Upstate Medical University, United States have published the research: Efficacy decrease of antiviral agents when administered to ongoing hepatitis C virus infections in cell culture, in the Journal: (JOURNAL)
  • what: The authors report the consequences of adding DAAs -4,4`-diylbis{1H-imidazole-5,2-diyl-[(2S)pyrrolidine-2,1-diyl][(2S)-3-methyl-1-oxobutane-1,2-diyl]}) dicarbamate) and sofosbuvir] or combinations of lethal mutagens, favipiravir and ribavirin, once the infection of Huh-7.5 cells by HCV p0 or its high fitness derivative HCV . . .

     

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