Tanshinone iia and hepatocellular carcinoma: a potential therapeutic drug

HIGHLIGHTS

  • who: Hu Li et al. from the United States Shanghai Jiao Tong University, China have published the Article: Tanshinone IIA and hepatocellular carcinoma: A potential therapeutic drug, in the Journal: (JOURNAL)
  • what: The main reason for the above mechanism is that the proportion of Smad7/ Smad3 is up-regulated, which inhibits the TGFb-mediated MET process .
  • how: The above data showed that TsIIA induced HCC apoptosis in part through the calcium-dependent apoptosis pathway . Previous laboratory data showed that the expression level of E-cadherin in HCC cells treated with TsIIA was increased . . .

     

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