HIGHLIGHTS
- who: Emma Hymel from the Department of Epidemiology, University of Nebraska Medical Center, Nebraska Medical Center, Omaha, NE, u20114395, USA have published the research work: Differential methylation patterns in lean and obese non-alcoholic steatohepatitis-associated hepatocellular carcinoma, in the Journal: (JOURNAL)
- what: The authors used previously generated mouse models of lean and obese HCC using a choline deficient/high trans-fat/fructose/cholesterol diet and a choline supplemented/high trans-fat/fructose/cholesterol diet respectively to evaluate differences in HCC progression in lean versus obese mice. The authors demonstrated that significant differential methylation exists . . .
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